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Prescription Weight-Loss Drugs

Only two weight-loss drugs, Xenical and Meridia, currently are approved for long-term use in the United States, with the FDA currently considering approval of a third, rimonabant (Acomplia / Zimulti).

The other drugs all are intended for short-term use, and you should read the description of their side-effects carefully.

Drug	Generic name	Method of Action
Acomplia	Rimonabant	CB-1 receptor antagonist. Blocks CB1 receptor in Endocannabinoid System, believed to play a critical role in the regulation of food intake and energy expenditure.
Xenical	Orlistat	Works in the intestines where it blocks some of the fat people eat from being absorbed and digested.
Meridia	Sibutramine	Decreases appetiite by inhibiting the reuptake of serotonin, norepinephrine, and dopamine in the brain.
Ionamin	Phentermine	Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Adipex-P	Phentermine	Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Phentermine	Phentermine	Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Bontril	Phendimetrazine	Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Didrex	Benzphetamine	Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite
Tenuate	diethylpropion	Stimulates central nervous system, increasing heart rate and blood pressure and decreasing appetite

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This is an independent news site reporting on prescription and over-the-counter diet drugs and on the more than 200 additional diet drugs currently in various stages of development. . Nothing on this site is intended to infringe on any trademarks. Nothing on this site is intended as medical advice. The information provided is for informational purposes only. Always consult a doctor or medical professional with questions regarding a medical condition.